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Others have reported when doing the 2 low dose method of getting the best results when they do a small dose in the morning on an empty stomach and then again 30 minutes before going to sleep on an empty stomach. They reported excellent sleep, and general feelings of well being, focus and energy during the day and depression was also decreased.

Generally however, most typical protocols recommend one time per day for convenience and so that patients don’t feel like they are a “pin cushion”.
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